Histoplasmosis - Search
  1. Histoplasmosis
    HistoplasmosisHuman disease
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  2. Histoplasmosis - Overview

    Verified Expert
    Also known as: caves disease
    A type of lung infection caused by inhaling fungus Histoplasma capsulatum spores. These are found in birds and bat droppings. Usually many people remain without symptoms but with weak immune system, they develop serious problems.
    Condition Highlight
    Urgent medical attention is usually recommended by healthcare providers
    Condition Highlight
    Certain types can be dangerous or life threatening
    How common is condition?
    Common (More than 200,000 cases per year in US)
    Is condition treatable?
    Treatable by a medical professional
    Does diagnosis require lab test or imaging?
    Requires lab test or imaging
    Time taken for recovery
    Can last several weeks or months
    Condition Highlight
    Can develop between ages 15-35, common over 65
    See more

    Causes

    Verified Expert

    Histoplasmosis is caused by inhalation of spores of histoplasma capsulatum which are found in places where birds and bats have roosted.

    The risk factors are high among persons working in:

    • Farms
    • Poultry
    • Pest control
    • Cave explorers
    • Children younger than age 2 and adults age above 55

    See more

    Symptoms

    Verified Expert
    Seek immediate medical attention if you experience symptoms.

    Most people will have no symptoms. In infants or persons with weaker immune system may develop symptoms like:

    • Fever
    • Headache
    • Dry cough/cough with blood in chronic phase
    • Chills
    • Muscle aches
    • Chest discomfort
    • Pain in the joints

    See more

    Treatment

    Verified Expert

    Symptoms of histoplasmosis may disappear without treatment in some people and others may need treatment to manage the infection.

    Medication

    Antifungals: These are used in management of moderate to severe cases.

    Amphotericin B . Itraconazole . Posaconazole . Isavuconazole

    See more
    histoplasmosis_en
    Microsoft Start Health

    Diagnosis

    Verified Expert
    One or more of these tests may be recommended by your medical provider.
    Diagnosis involves the tests to confirm the presence of fungus and the extent to which the lung has been damaged.

    Common tests & procedures

    Blood test: To check for antibodies that indicate histoplasmosis.

    Polymerase chain reaction (PCR): These are used for detection of antigens in blood samples.

    Bacteria culture test: To check for the presence of any other organisms in the body.

    X-ray: To check the condition of lungs.

    CT scan: CT scan of chest is performed to analyze the condition of the chest and lungs.

    Histopathology and Cytology: to detect characteristic pathology and organisms by staining

    See more
    Source: Focus Medica. For informational purposes only. Consult a medical professional for advice. | Disclaimer: Opinions are from external health professionals and should not be considered as Microsoft's opinion or a substitute for professional help. Consult a health professional for medical advice.
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  2. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/...

    Histoplasmosis - Symptoms & causes - Mayo Clinic

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  3. Cleveland Clinic
    https://my.clevelandclinic.org/health/…

    Histoplasmosis: Causes, Symptoms, Diagnosis

    WEBMar 8, 2023 · Histoplasmosis is a fungal infection of the lungs caused by breathing in the fungus Histoplasma capsulatum. Learn about the types, risk factors, complications and treatment of this disease from …

  4. Wikipedia
    https://en.wikipedia.org/wiki/Histoplasmosis

    Histoplasmosis - Wikipedia

  5. Histoplasmosis
    Data fromBritannica
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    Pulmonary Histoplasmosis
    Disseminated Histoplasmosis
    Antifungal Drugs
    Histoplasmosis, infection with the fungus Histoplasma capsulatum, occurring in humans and other animals. The disease is contracted by the inhalation of dust containing spores of the fungus. H. capsulatum prefers moist, shady...see more

    Insight :Histoplasma capsulatum is a thermal dimorph, growing as mold or yeast

    Insight :The fungus is prevalent in the Ohio and Mississippi River valleys

    Insight :Histoplasmosis is often asymptomatic, but symptoms can vary widely

    Insight :The microconidia spores of H. capsulatum cause infection in humans

    Quiz :What is the primary way humans contract histoplasmosis?

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  6. CDC
    https://www.cdc.gov/histoplasmosis

    Histoplasmosis | Histoplasmosis | CDC

  7. CDC
    https://www.cdc.gov/histoplasmosis/about

    About Histoplasmosis | Histoplasmosis | CDC

  8. CDC
    https://www.cdc.gov/histoplasmosis/hcp/clinical-overview/index.html

    Clinical Overview of Histoplasmosis | Histoplasmosis | CDC

  9. The Merck Manuals
    https://www.merckmanuals.com/.../fungi/histoplasmosis

    Histoplasmosis - Histoplasmosis - Merck Manual Professional …

  10. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/...

    Histoplasmosis - Diagnosis & treatment - Mayo Clinic

  11. WebMD
    https://www.webmd.com/a-to-z-guides/histoplasmosis

    Histoplasmosis Fungal Infection: Signs, Causes, and Treatment

  12. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK448185

    Histoplasmosis - StatPearls - NCBI Bookshelf

    WEBAug 8, 2023 · Introduction. Histoplasma capsulatum (Hc) is a dimorphic fungus present worldwide in pockets of endemicity particularly associated with river valleys. The endemic regions in the United States are Ohio …

  13. Healthline
    https://www.healthline.com/health/histoplasmosis

    Histoplasmosis: Cause, Types & Complications - Healthline

  14. MedlinePlus
    https://medlineplus.gov/histoplasmosis.html

    Histoplasmosis: MedlinePlus

  15. UpToDate
    https://www.uptodate.com/contents/diagnosis-and...

    Diagnosis and treatment of pulmonary histoplasmosis

  16. The Merck Manuals
    https://www.merckmanuals.com/.../histoplasmosis

    Histoplasmosis - Histoplasmosis - Merck Manual Consumer Version

  17. CDC
    https://www.cdc.gov/histoplasmosis/causes

    How People Get Histoplasmosis | Histoplasmosis | CDC

  18. Verywell Health
    https://www.verywellhealth.com/histoplasmosis-7111772

    Histoplasmosis: Symptoms, Causes, and Treatment

  19. American Lung Association
    https://www.lung.org/lung-health-diseases/lung...

    Histoplasmosis Symptoms and Diagnosis - American Lung …

  20. Medical News Today
    https://www.medicalnewstoday.com/articles/318078

    Histoplasmosis: Causes, risk factors, and treatment

  21. UpToDate
    https://www.uptodate.com/contents/search?search=Histoplasmosis

    Histoplasmosis - UpToDate

  22. CDC
    https://www.cdc.gov/histoplasmosis/signs-symptoms/index.html

    Symptoms of Histoplasmosis | Histoplasmosis | CDC

  23. American Lung Association
    https://www.lung.org/.../histoplasmosis

    Histoplasmosis | American Lung Association

  24. American Academy of Ophthalmology
    https://www.aao.org/eye-health/diseases/what-is-histoplasmosis

    What Is Histoplasmosis? - American Academy of Ophthalmology